Lymph node (LN) is a key tissue in the pathophysiology of mature blood cancers, especially for chronic lymphocytic leukemia (CLL).Within the multiple de-regulated pathways affecting CLL homeostasis, the CC-chemokine receptor 7 (CCR7) grants homing of CLL cells into the LN where protective environments foster tumor progression.To cover the lack of s
BACKGROUND:With a conservatively estimated 1 million cases of leptospirosis worldwide and a 5-10% fatality rate, the rapid diagnosis of leptospirosis leading to effective clinical and public health decision making is of high importance, and yet remains a challenge.METHODOLOGY:Based on parallel, population-based studies in two leptospirosis-endemic
Carcinoarcoma of breast is rare tumor with aggressive behaviour and poor prognosis.Histologically it is biphasic tumor with epithelial and mesenchymal component.Very few cases of carcinosarcoma, its presentation and behaviour have been reported in Oils the literature, and due to its bizarre behaviour it is a diagnostic challenge to pathologist and